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Wegovy benefits consistent regardless of frailty level

Дата публикации: 17-09-2026 13:41:39

In a new analysis of the SELECT trial published in JAMA Cardiology, semaglutide 2.4 mg improved clinical outcomes compared with placebo regardless of frailty level.For the analysis, the 17,604 patients (mean age, 61.6 years; 72.3% men) from SELECT, a trial that demonstrated semaglutide 2.4 mg (Wegovy, Novo Nordisk) reduced risk for major cardiovascular outcomes by 20% compared with placebo, were stratified into three categories according to a 31-item frailty index: not frail (31%), more frail (47%) and most frail (22%).“Practice is currently highly variable, which is due, in part, to

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