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SpaceX
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СпутникиРНSpaceXРоскосмосNASAIn Reply I appreciate the opportunity to respond to the comments raised by Yuji regarding our recent article and rectify possible miscommunication of our findings and their implications. In brief, our study of adolescent and young adult patients with cancer who accessed medical assistance in dying (MAiD) in Alberta, Canada, identified that Edmonton Symptom Assessment System−revised scores increased significantly during the year preceding MAiD provision. Given our small study size of 34 patients, we acknowledged that our analyses of symptom trajectories and potential phase segmentation were exploratory in nature and intended solely to visualize patterns in symptom burden over time. Nevertheless, as we observed rapid rises beginning at approximately month 5 prior to MAiD provision, we suggested current provincial metrics for specialist palliative care, which define early access as occurring within 3 months of death, may be insufficient for this distinct population as symptom burden peaked before that time point. Accordingly, we proposed that novel approaches are warranted to facilitate timely specialist palliative care referrals, such as the integration of automated referral pathways triggered by advanced disease diagnosis or the attainment of a predefined patient-reported symptom threshold.